Mediators of Inflammation / 2012 / Article / Tab 1

Research Article

Pegylated Arginine Deiminase Downregulates Colitis in Murine Models

Table 1

IL-10 deficient-mice: comparison of inflammatory markers in plasma and colonic explants in IL-10-deficient (IL-10−/−) mice treated with DSS and ADI-PEG versus sham controls. , , and   .

PlasmaColonic explant + LPS

Inflammatory markersIL-6 (pg/mL)IL-12p40 (pg/mL)SAA ( g/mL)NO (μM)IL-6 (ng/mL)IL-12p40 (pg/mL)
Control
ADI
DSS
DSS + ADI-PEG (low dose)
DSS + ADI-PEG (high dose)

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