Review Article

Usefulness of the Vitreous Fluid Analysis in the Translational Research of Diabetic Retinopathy

Figure 2

Results obtained by using the fluorescence-based difference gel electrophoresis (DIGE) strategy showing the higher abundance of hemopexin in the vitreous fluid of diabetic patients with DME in comparison with Nondiabetic controls and PDR patients. (a) Three-dimensional images of the hemopexin spot corresponding to the image of a control (C), DME, and PDR samples. (b) Standardised abundance plot for hemopexin displaying the log of abundance observed for the spot in each of the four gel images corresponding to control (C), DME, and PDR samples. The line links the average abundance values for each group of samples (crosses). Student’s test results in a significant increase ( ) in DME sample in comparison with either C or PDR sample.
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(a)
872978.fig.002b
(b)