Heavy Ethanol Intoxication Increases Proinflammatory Cytokines and Aggravates Hemorrhagic Shock-Induced Organ Damage in Rats

<table>Changes in (a) mean arterial pressure, (b) heart rate, (c) serum ethanol concentration, and (d) hemoglobin following hemorrhagic shock in rats. *<svg height="11.375" id="M9" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> for the HS group compared with the Vehicle group. <sup>+</sup><svg height="11.375" id="M10" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> for the Ethanol group compared with the Vehicle group. <sup>#</sup><svg height="11.375" id="M11" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> for the Ethanol + HS group compared with the HS group. </table>

Mediators of Inflammation

fig2

Figure 2

Figure 2: Heavy Ethanol Intoxication Increases Proinflammatory Cytokines and Aggravates Hemorrhagic Shock-Induced Organ Damage in Rats 