Association of Serum Adiponectin, Leptin, and Resistin Concentrations with the Severity of Liver Dysfunction and the Disease Complications in Alcoholic Liver Disease
Table 12
Independent predictors of advanced liver dysfunction (MELD ≥ 20) and ALD complications (multivariable analysis)*.
Complication of ALD
Variable
value
Adjusted OR (95% CI)
AUC (95% CI)
SE
MELD ≥ 20
Acrp30
0.001
1.013 (1.005–1.022)
0.873 (0.807–0.923)
0.041
CRP
0.004
1.017 (1.005–1.029)
WBC
0.030
1.119 (1.011–1.238)
HE
0.0009
8.184 (2.373–28.224)
Ascites
Acrp30
0.050
1.009 (1.000–1.019)
0.902 (0.840–0.946)
0.028
albumin
0.0001
0.095 (0.030–0.300)
ALT
0.003
0.978 (0.964–0.993)
INR
0.003
22.137 (2.780–176.287)
RBC
0.021
2.962 (1.177–7.452)
HE
Acrp30
0.010
1.011 (1.003–1.019)
0.830 (0.757–0.889)
0.048
albumin
0.050
0.323 (0.105–0.998)
T-bilirubin
0.001
1.116 (1.045–1.193)
AUC: area under the ROC curve, CI: confidence interval, OR: Odds ratio, SE: standard error, HE: hepatic encephalopathy.
