p38/AP-1 Pathway in Lipopolysaccharide-Induced Inflammatory Responses Is Negatively Modulated by Electrical Stimulation
Figure 2
Effect of nanocurrent-generating ACPs (NGACPs) treatment on the production of inflammatory mediators. ((a), (b), and (c)) The levels of NO and PGE2 were determined using a Griess assay and EIA with culture supernatants from RAW264.7 cells or peritoneal macrophages that had been treated with NGACP and LPS (1 g/mL) or pam3CSK (10 g/mL) for 6 or 24 h (NO and PGE2, resp.). (d) Morphological alterations in RAW264.7 cells and HEK293 cells were photographed using a digital camera. (e) The viability of RAW264.7 and HEK293 cells was determined using an MTT assay. * and ** compared to control.
