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Mediators of Inflammation
Volume 2013, Article ID 187940, 6 pages
http://dx.doi.org/10.1155/2013/187940
Clinical Study

Relationships of Adiponectin with Markers of Systemic Inflammation and Insulin Resistance in Infants Undergoing Open Cardiac Surgery

1Department of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, No. 15, Changle West Road, Xi’an, Shaanxi 710032, China
2Department of Oral Anatomy and Physiology and TMD, School of Stomatology, Fourth Military Medical University, Xi’an, Shaanxi 710032, China

Received 4 August 2012; Accepted 22 May 2013

Academic Editor: Celeste C. Finnerty

Copyright © 2013 Yukun Cao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. O. Butler, I. F. Btaiche, and C. Alaniz, “Relationship between hyperglycemia and infection in critically ill patients,” Pharmacotherapy, vol. 25, no. 7, pp. 963–976, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. I. Vanhorebeek, L. Langouche, and G. van den Berghe, “Glycemic and nonglycemic effects of insulin: how do they contribute to a better outcome of critical illness?” Current Opinion in Critical Care, vol. 11, no. 4, pp. 304–311, 2005. View at Publisher · View at Google Scholar · View at Scopus
  3. G. van den Berghe, P. Wouters, F. Weekers et al., “Intensive insulin therapy in critically ill patients,” The New England Journal of Medicine, vol. 345, no. 19, pp. 1359–1367, 2001. View at Publisher · View at Google Scholar · View at Scopus
  4. G. van den Berghe, A. Wilmer, G. Hermans et al., “Intensive insulin therapy in the medical ICU,” The New England Journal of Medicine, vol. 354, no. 5, pp. 449–461, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. R. Zheng, C. Gu, Y. Wang et al., “Impacts of intensive insulin therapy in patients undergoing heart valve replacement,” Heart Surgery Forum, vol. 13, no. 5, pp. E292–E298, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. H. Sato, G. Carvalho, T. Sato, R. Lattermann, T. Matsukawa, and T. Schricker, “The association of preoperative glycemic control, intraoperative insulin sensitivity, and outcomes after cardiac surgery,” Journal of Clinical Endocrinology and Metabolism, vol. 95, no. 9, pp. 4338–4344, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. H. Aebert, S. Kirchner, A. Keyser et al., “Endothelial apoptosis is induced by serum of patients after cardiopulmonary bypass,” The European Journal of Cardio-thoracic Surgery, vol. 18, no. 5, pp. 589–593, 2000. View at Publisher · View at Google Scholar · View at Scopus
  8. T. Asahara, H. Masuda, T. Takahashi et al., “Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization,” Circulation Research, vol. 85, no. 3, pp. 221–228, 1999. View at Google Scholar · View at Scopus
  9. H. Wang, O. Bloom, M. Zhang et al., “HMG-1 as a late mediator of endotoxin lethality in mice,” Science, vol. 285, no. 5425, pp. 248–251, 1999. View at Publisher · View at Google Scholar · View at Scopus
  10. K. J. Tracey, Y. Fong, D. G. Hesse et al., “Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia,” Nature, vol. 330, no. 6149, pp. 662–664, 1987. View at Google Scholar · View at Scopus
  11. C.-H. Gu, Q. Cui, Y.-Y. Wang et al., “Effects of insulin therapy on inflammatory mediators in infants undergoing cardiac surgery with cardiopulmonary bypass,” Cytokine, vol. 44, no. 1, pp. 96–100, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. F. Ziemke and C. S. Mantzoros, “Adiponectin in insulin resistance: lessons from translational research,” The American Journal of Clinical Nutrition, vol. 91, no. 1, pp. 258S–261S, 2010. View at Publisher · View at Google Scholar · View at Scopus
  13. M. Lehrke, U. C. Broedl, I. M. Biller-Friedmann et al., “Serum concentrations of cortisol, interleukin 6, leptin and adiponectin predict stress induced insulin resistance in acute inflammatory reactions,” Critical Care, vol. 12, no. 6, article R157, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. Y.-L. Liu, H. Bi, S.-M. Chi et al., “The effect of compound nutrients on stress-induced changes in serum IL-2, IL-6 and TNF-α levels in rats,” Cytokine, vol. 37, no. 1, pp. 14–21, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. C. S. Mantzoros, T. Li, J. E. Manson, J. B. Meigs, and F. B. Hu, “Circulating adiponectin levels are associated with better glycemic control, more favorable lipid profile, and reduced inflammation in women with type 2 diabetes,” Journal of Clinical Endocrinology and Metabolism, vol. 90, no. 8, pp. 4542–4548, 2005. View at Publisher · View at Google Scholar · View at Scopus
  16. N. Soebijanto and S. Waspadji, “Adiponectin levels and its role in insulin resistance among adult women with metabolic syndrome,” Acta medica Indonesiana, vol. 42, no. 4, pp. 187–191, 2010. View at Google Scholar · View at Scopus
  17. G. S. Hotamisligil, “Inflammatory pathways and insulin action,” International Journal of Obesity, vol. 27, supplement 3, pp. S53–S55, 2003. View at Publisher · View at Google Scholar · View at Scopus
  18. A. Shah, N. Mehta, and M. P. Reilly, “Adipose inflammation, insulin resistance, and cardiovascular disease,” Journal of Parenteral and Enteral Nutrition, vol. 32, no. 6, pp. 638–644, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. T. Yamauchi, J. Kamon, H. Waki et al., “The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity,” Nature Medicine, vol. 7, no. 8, pp. 941–946, 2001. View at Publisher · View at Google Scholar · View at Scopus
  20. C. Weyer, T. Funahashi, S. Tanaka et al., “Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia,” Journal of Clinical Endocrinology and Metabolism, vol. 86, no. 5, pp. 1930–1935, 2001. View at Publisher · View at Google Scholar · View at Scopus
  21. J. Kremen, M. Dolinkova, J. Krajickova et al., “Increased subcutaneous and epicardial adipose tissue production of proinflammatory cytokines in cardiac surgery patients: possible role in postoperative insulin resistance,” Journal of Clinical Endocrinology and Metabolism, vol. 91, no. 11, pp. 4620–4627, 2006. View at Publisher · View at Google Scholar · View at Scopus