Mediators of Inflammation / 2013 / Article / Tab 4

Clinical Study

Cytokines and Chemokines as Biomarkers of Community-Acquired Bacterial Infection

Table 4

Kinetics of inflammatory molecules in patients with bacterial infection during antibiotic therapy.

Analyte (pg/mL) Day 1Day 3Day 7Control value

IL-1Ra11,618*3,2472,6041,544<0.001
(42,790)(11,492)(8,607)(8,768)
IL-222.5*21.4*19.5*11.9<0.013
(36.5)(57.4)(71.2)(26.1)
IL-639.1*1.90.40.4<0.001
(1,597)(150)(95.8)(0.0)
IL-826.6*21.214.66.9<0.039
(350)(648)(58)(54)
TNF- 10.8*5.54.50.6<0.020
(61.0)(31.2)(16.8)(25.8)
MCP-1326187231205n.s.
(7,524)(210)(287)(279)
MIP-1 91.0*76.860.454.6<0.025
(1,699)(275)(161)(91.2)

Data are presented as median (range); n.s.: not significant; * , time point versus control.

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