Endobronchial Perfluorocarbon Reduces Inflammatory Activity before and after Lung Transplantation in an Animal Experimental Model
Figure 1
Apoptosis and inflammatory activity during lung preservation. (a) Effects of different periods of lung preservation on pulmonary lipid peroxidation. Using the TBARS assay, there was a significant decrease in lipid peroxidation at 3 hours of preservation in the PFC7 group (*). The control group showed a significant increase in lipid peroxidation at 6 h (#). Data are means ± standard deviation of the mean (). (b) Caspase 3 activity at different times of lung preservation. There is a significant increase in caspase 3 activity in the control group at 6, 12, and 24 hours (*). Data are means ± SD of the mean. (c) NF-B expression (subunit p65) in the lung tissue at different times of lung preservation. A significant increase in the expression of p65 was observed in the control group at 3, 12, and 24 hours compared with the animals that used PFC (*). PFC7 reduced the expression of p65 at 24 hours of preservation compared with PFC3 (#).
