Oxidized LDL Induces Alternative Macrophage Phenotype through Activation of CD36 and PAFR
Figure 1
oxLDL preferentially increases LPS-induced anti-inflammatory cytokines. THP-1 monocytes were differentiated into macrophages with PMA, followed by treatment with oxLDL (20 μg/mL) for 24 h, and then stimulated with LPS (100 ng/mL) for an additional 24 h. Cytokines concentration in the supernatant was measured by ELISA. Data are presented as mean ± SEM of four independent experiments. * versus LPS-stimulated cells.
