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Mediators of Inflammation
Volume 2013, Article ID 231351, 13 pages
http://dx.doi.org/10.1155/2013/231351
Research Article

Lipoxin A4 Preconditioning and Postconditioning Protect Myocardial Ischemia/Reperfusion Injury in Rats

1Department of Cardiovascular and Thoracic Surgery, The 2nd Affiliated Hospital & Yuying Children’s Hospital of Wenzhou Medical University, 109 College Western Road, Wenzhou 325027, China
2Department of Cardiovascular Medicine, The 2nd Affiliated Hospital & Yuying Children’s Hospital of Wenzhou Medical University, 109 College Western Road, Wenzhou 325027, China

Received 10 April 2013; Revised 15 June 2013; Accepted 16 June 2013

Academic Editor: Fulvio D'Acquisto

Copyright © 2013 Qifeng Zhao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Figure 1: Chemical structure of LXA4. Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function. 5(S),6(R),15(R)-LipoxinA4 (5(S),6(R),15(R)-LXA4) is derived from the aspirin- triggered formation of 15(R)-HETE from arachidonic acid. Formula Weight: 352.5.

According to DNA sequence of various indexes, Primer 3.0 software was used to design Na+-K+-ATPase and Cx43 primer. GAPDH is control gene. Primer sequences of Na+-K+-ATPase and Cx43 were as shown in Supplementary Table 1.

  1. Supplementary Figure
  2. Supplementary Table