Plasma Granzyme B in ST Elevation Myocardial Infarction versus Non-ST Elevation Acute Coronary Syndrome: Comparisons with IL-18 and Fractalkine
Table 1
Demographic data and clinicopathological parameters of the studied groups.
Groups
Controls
ACS
Factor/
12
36
Age (years)
47.92 ± 1.42
50.4 ± 0.5
NS
Sex (M/F)
10/2
26/10
NS
BMI (kg/m2)
28 ± 0.7
28.4 ± 0.3
NS
TAG (mmol/L)
0.96 ± 0.05
1.26 ± 0.02
<0.01
TC (mmol/L)
4.4 ± 0.14
5.23 ± 0.08
<0.001
HDL-C (mmol/L)
1.11 ± 0.04
0.92 ± 0.02
<0.01
LDL-C (mmol/L)
2.82 ± 0.09
3.65 ± 0.06
<0.001
LDL-C/HDL-C
2.6 ± 0.1
4.1 ± 0.1
<0.001
TC/HDL-C
4 ± 0.1
5.8 ± 0.2
<0.001
hsCRP (mg/L)
0.7 ± 0.1
9.4 ± 0.6
<0.001
GZB (pg/L)
122.3 ± 4.2
193.4 ± 13.3
<0.001
IL-18 (pg/mL)
53.7 ± 2.8
94.5 ± 3.7
<0.001
FKN (pg/mL)
388.8 ± 28.8
637.2 ± 22.7
<0.001
Results are mean ± SEM. HDL-C: high density lipoprotein cholesterol; LDL-C: low density lipoprotein cholesterol; NS: not significant; TAG: triacylglycerol; TC: total cholesterol.
