Table 1: Anthropometric and metabolic characteristics of the study groups.

 NGTT2DM
NGT-NWNGT-OBT2DM-NWT2DM-OB

N (M/F)46 (15/31)42 (20/22)37 (11/26)43 (18/25)
Age (year)58.54 ± 5.9659.10 ± 7.4361.65 ± 6.9660.86 ± 7.22
Weight (kg)55.83 ± 5.7468.79 ± 8.04b55.54 ± 6.2769.30 ± 8.51f
BMI (kg/cm2)22.36 ± 1.7527.81 ± 3.10b22.97 ± 1.4727.78 ± 2.25f
WC (cm)78.17 ± 5.7291.69 ± 5.42b80.38 ± 6.2091.81 ± 5.43f
WHR0.86 ± 0.040.92 ± 0.05b0.87 ± 0.050.91 ± 0.04f
SBP (mm Hg)118.41 ± 9.45122.79 ± 9.61133.46 ± 15.65bd127.43 ± 14.45bd
DBP (mm Hg)74.20 ± 6.9974.67 ± 7.2574.49 ± 10.0975.52 ± 8.81ace
FPG (mmol/L)5.25 ± 0.335.40 ± 0.437.28 ± 1.34bd7.46 ± 1.13bd
2hPG (mmol/L)6.28 ± 1.036.00 ± 1.1413.58 ± 2.99bd13.09 ± 3.30bd
FINS (mU/L)5.61 ± 2.588.87 ± 4.76a7.58 ± 3.8812.27 ± 7.04bdf
HbA1c (%)5.49 ± 0.325.57 ± 0.356.79 ± 0.78bd6.79 ± 0.80bd
TC (mmol/L)4.43 ± 0.914.82 ± 1.00a4.59 ± 0.844.85 ± 0.92a
TG (mmol/L)1.07 ± 0.511.48 ± 0.84a1.50 ± 0.80a2.04 ± 1.37bce
HDL-c (mmol/L)1.43 ± 0.271.28 ± 0.32a1.31 ± 0.351.14 ± 0.23bce
LDL-c (mmol/L)2.47 ± 0.692.84 ± 0.78a2.55 ± 0.642.82 ± 0.70a
PGRN (ng/mL)148.69 ± 55.27183.79 ± 61.63a195.59 ± 50.47b225.22 ± 34.39bde
IL-6 (pg/mL)2.57 ± 1.783.73 ± 2.694.46 ± 3.37a7.68 ± 3.14bde
hsCRP (mg/dL) 0.24 ± 0.13 0.35 ± 0.26a0.32 ± 0.18a0.43 ± 0.29bdf
HOMA-IR1.32 ± 0.642.12 ± 1.14a2.43 ± 1.22b4.07 ± 2.49bdf
HOMA-β93.42 ± 39.6090.90 ± 44.2763.51 ± 32.09bd43.96 ± 26.08bde

Data are presented as means ± SD. NGT: normal glucose tolerance; T2DM: type 2 diabetes mellitus; NW: normal weight; OB: obesity; BMI: body mass index; WC: waist circumference; WHR: waist hip ratio; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; 2hPG: 2h postchallenge plasma glucose; FINS: fasting serum insulin; HOMA-IR: Homeostasis Model Assessment for insulin resistance; HOMA-β: Homeostasis Model Assessment for beta-cell function; TC: total cholesterol; TG: triglyceride; HDL-c: high-density lipoprotein-cholesterol; LDL-c: low-density lipoprotein-cholesterol; hs-CRP: high-sensitivity C-reaction protein. aP 0.05 compared with NGT-NW, bP < 0.01 compared with NGT-NW; cP 0.05 compared with NGT-OB, dP < 0.01 compared with NGT-OB, eP 0.05 compared with T2DM-NW, and fP < 0.01 compared with T2DM-NW.