Mediators of Inflammation

Research Article

Plasma Progranulin Concentrations Are Increased in Patients with Type 2 Diabetes and Obesity and Correlated with Insulin Resistance

Table 2

Univariate associations between plasma PGRN levels and metabolic parameters.
　r P value
Weight (kg)0.175 0.023
BMI (kg/m2)0.286 <0.001
WC (cm)0.191 0.013
WHR0.042 0.589
SBP (mmHg)0.256 0.001
DBP (mmHg)0.138 0.074
FPG (mmol/L)0.348 <0.001
2hPG (mmol/L)0.292 <0.001
FINS (mU/L)0.172 0.025
HbA1c (%)0.276 <0.001
TC (mmol/L)0.126 0.103
TG (mmol/L)0.221 0.004
HDL-c (mmol/L)−0.110 0.156
LDL-c (mmol/L)0.059 0.450
IL-6 (pg/mL)0.383 <0.001
HOMA-IR0.228 0.003
HOMA-β−0.225 0.003
WHR: waist hip ratio; SBP: systolic blood pressure; DBP: diastolic blood pressure; HOMA-IR: Homeostasis Model Assessment for insulin resistance; HOMA-β: Homeostasis Model Assessment for beta-cell function; TC: total cholesterol; TG: triglyceride; HDL-c: high-density lipoprotein-cholesterol; LDL-c: low-density lipoprotein-cholesterol.