PD-L1 Blockade Attenuated Sepsis-Induced Liver Injury in a Mouse Cecal Ligation and Puncture Model
Immunohistochemical staining of liver tissues using anti-PD-L1 Abs. Representative patterns of expression of PD-L1 in liver tissues were shown in sham ((a) and (b)) and CLP mice ((c) and (d)). Positive cells were stained brown. The black arrows indicated PD-L1+ cells. Strong and widespread PD-L1 expression was examined as shown in panel (c) and (d), whereas sham groups showed undetectable signal. Original magnification ×200 for (a) and (c) and ×400 for (b) and (d).
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