Research Article

PD-L1 Blockade Attenuated Sepsis-Induced Liver Injury in a Mouse Cecal Ligation and Puncture Model

Figure 1

Immunohistochemical staining of liver tissues using anti-PD-L1 Abs. Representative patterns of expression of PD-L1 in liver tissues were shown in sham ((a) and (b)) and CLP mice ((c) and (d)). Positive cells were stained brown. The black arrows indicated PD-L1+ cells. Strong and widespread PD-L1 expression was examined as shown in panel (c) and (d), whereas sham groups showed undetectable signal. Original magnification ×200 for (a) and (c) and ×400 for (b) and (d).
361501.fig.001a
(a)
361501.fig.001b
(b)
361501.fig.001c
(c)
361501.fig.001d
(d)