Research Article

The Mechanism of Sevoflurane Preconditioning-Induced Protections against Small Intestinal Ischemia Reperfusion Injury Is Independent of Mast Cell in Rats

Figure 4

MPO activities and ICAM-1 protein expression in intestine mucosa after IIR injury. SH group (Sham-operated group), IIR group (75 min intestinal ischemia and 2 h reperfusion), IIR + CP group (IIR group + Compound 48/80 1 mg/kg), IIR + CS group (50 mg/kg cromolyn sodium treated IIR group), IIR + CS + CP group (50 mg/kg cromolyn sodium treated IIR group + Compound 48/80 1 mg/kg), SEV + IIR group (2.3% sevoflurane pretreated IIR group), and SEV + IIR + CP group (2.3% sevoflurane pretreated IIR group + Compound 48/80 1 mg/kg). Bar graph (a) quantified MPO activities in intestinal mucosa ( ). Representative band of ICAM-1 protein expressions is displayed in (b). Bar graphs (c) quantified ICAM-1 protein expressions ( ). Results are expressed as Mean ± SEM. versus SH group, versus IIR group, versus IIR + CP group, versus IIR + CS group, and versus SEV + IIR group.
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(a)
378703.fig.004b
(b)
378703.fig.004c
(c)