Natural Antioxidant-Isoliquiritigenin Ameliorates Contractile Dysfunction of Hypoxic Cardiomyocytes via AMPK Signaling Pathway

Figure 1

Contractile properties of cardiomyocytes from vehicle and ISL treatment after being exposed to hypoxia. (a) Resting cell length; (b) peak shortening (PS, normalized to cell length); (c) maximal velocity of shortening (+𝑑𝐿/𝑑𝑡); (d) relengthening (−𝑑𝐿/𝑑𝑡); (e) time-to-peak shortening (TPS); (f) time-to-90% relengthening (TR90). Values are means ± SE, 𝑛=50--60 cells per group, ^∗𝑃<0.05 versus normoxia vehicle; ^†𝑃<0.05 versus hypoxia vehicle.

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