Regulation and Prognostic Relevance of Symmetric Dimethylarginine Serum Concentrations in Critical Illness and Sepsis

Table 5

Uni- and multivariate Cox regression analyses for SDMA levels at admission to predict overall mortality.

Parameter	Unadjusted HR (95%-CI)	𝑃 value	Adjusted HR (95%-CI)	𝑃 value
SDMA	1.275 (1.067–1.524)	0.007	1.357 (1.088–1.692)	0.007
Protein	0.965 (0.948–0.982)	<0.001	0.973 (0.954–0.992)	0.006
INR	1.630 (1.226–2.168)	0.001	1.410 (0.997–1.994)	0.05
Lactate	1.133 (1.054–1.217)	0.001	1.122 (1.042–1.207)	0.002
Creatinine	1.009 (0.944–1.079)	NS	—	NS
White blood cell count	0.989 (0.967–1.012)	NS	—	NS
C-reactive protein	1.001 (0.999–1.004)	NS	—	NS