Mediators of Inflammation / 2013 / Article / Fig 1

Research Article

High Intestinal and Systemic Levels of Interleukin-23/T-Helper 17 Pathway in Chinese Patients with Inflammatory Bowel Disease

Figure 1

The mRNA expression of IL-23/Th17 pathway related genes in IBD patients. (a) and (b) The levels of IL-12p40 and TL1A mRNA expression were higher in UC patients than healthy controls ( ). (c) and (d) There was a highly significant increase in the expression of JAK2 and IL-23R in patients with UC and CD as compared to healthy controls ( , for both comparisons), but no significant difference was observed between UC and CD patients. The level of mRNA expression was normalized to that of β-actin mRNA expression. Horizontal lines represent median values for each group and NS indicate no significance.

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