The Role of Mcl-1 in S. aureus-Induced Cytoprotection of Infected Macrophages
Figure 3
Exposure to S. aureus triggers Mcl-1 production in vivo. (a) Immunoblot reveals increase in Mcl-1 expression in inflamed joints derived from three individual S. aureus-infected mice (Sa) in comparison to noninfected animals (Veh.). A representative immunoblot from three separate experiments is shown. (b) The expression of Mcl-1 in joints correlates with infection score and bacterial load determined as described in Section 2. Data represents Mcl-1 levels in noninfected (Veh.; ) and S. aureus-infected (Sa; ) animals, obtained by densitometric analyses of western blots.
