Metformin Inhibits Expression and Secretion of PEDF in Adipocyte and Hepatocyte via Promoting AMPK Phosphorylation
Figure 1
The mRNA expression of the key enzymes regulating gluconeogenesis and fatty acid synthesis in the liver. SD rats were fed a normal chow diet (NC group, ) or a high fat diet () for 15 weeks; then the high-fat-diet rats were gavaged saline (HF group, ) or metformin 400 mg/kg/d (MET group, ) for 4 weeks. , compared with NC group. , compared with HF group.
