Hypothermia Reduces Toll-Like Receptor 3-Activated Microglial Interferon-β and Nitric Oxide Production
Figure 1
Effect of hypothermic culture on IFN-β production by poly(I:C)-stimulated mouse microglia. Mouse microglia ( cells/well) were cultured with 100 μg/mL poly(I:C) under hypothermic (33°C) and normothermic (37°C) conditions for 48 h. IFN-β levels in culture supernatants were measured by ELISA. Data are expressed as (). * compared with 37°C.
