A Subanesthetic Dose of Isoflurane during Postconditioning Ameliorates Zymosan-Induced Neutrophil Inflammation Lung Injury and Mortality in Mice

Figure 4

NF-κB activation caused by ZY in lung at 24 hrs was reduced by 0.7% ISO treatment. Representative western blot for cytoplasmic IκB degradation (a) and nuclear translocation of NF-κB p65 (b). Results were quantified as arbitrary densitometry units ((c) and (d)). (e) NF-κB DNA-binding activity as assayed by optical density. The animals were treated as shown in Figure 1(a). Data represent means ± SD (𝑛=10mice per group).^∗𝑃<0.05versus sham + vehicle;^#𝑃<0.05versus ZY + vehicle.

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