TNF and TNF Receptor Superfamily Members in HIV infection: New Cellular Targets for Therapy?

<table>TNF signaling mimicking by HIV proteins. Early expressed HIV proteins Vpr, Tat, and Nef mimic TNF-alpha as they activate TNF-alpha governing signaling pathways to enhance HIV replication in infected cells.</table>

Mediators of Inflammation

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Figure 2

Figure 2: TNF and TNF Receptor Superfamily Members in HIV infection: New Cellular Targets for Therapy? 