Research Article

NF- B Inhibition after Cecal Ligation and Puncture Reduces Sepsis-Associated Lung Injury without Altering Bacterial Host Defense

Figure 6

Treatment with BMS-345541 does not affect bacterial phagocytosis. (a) Phagocytosis of GFP-labeled E. coli by RAW264.7 macrophages was measured by counting fluorescent cells at 1 hour after adding bacteria. BMS-345541 and LPS were added to culture medium 1 hour prior to bacteria. (b) Cells were obtained by peritoneal lavage at 3 hours after CLP and bacterial phagocytosis was measured as described above. Results are presented as mean ± SE from 3 independent experiments.