Research Article

Marked Independent Relationship between Circulating Interleukin-6 Concentrations and Endothelial Activation in Rheumatoid Arthritis

Table 3

Independent associations between cardiovascular risk factors and the endothelial score when entered into the same model.

CharacteristicsPartial

eGFR*0.2030.005
ESR*0.1640.03
IL-6*0.392<0.0001
Prednisone use0.1870.01

Model 0.272ā€‰

Risk factors (except for diastolic blood pressure and disease duration because of collinearity with hypertension and number of deformed joints, resp.) that were associated with endothelial activation in previous analyses together with age, sex, and other cardiovascular risk factors (see footnote of Table 2) were entered into the model. Only results on those risk factors that remained independently associated ( ) with the endothelial activation score are shown. EGFR: estimated glomerular filtration rate; ESR: erythrocyte sedimentation rate; IL-6: interleukin-6. *Logarithmically transformed.