|
| Drug | Indications |
|
| Antimetabolites |
| Methotrexate | Noninfectiouschronic uveitis, ocular inflammation, ocular sarcoidosis |
| Azathioprine | Chronic uveitis, Behcet’s, choroidal neovascularization, ocular cicatricial pemphigoid, retinal vasculitis, serpiginous choroiditis |
| Mycophenolate mofetil | Chronic uveitis, noninfectious ocular inflammation, refractory uveitis, scleritis |
| Leflunomide | Sarcoidosis |
|
| Alkylating agents |
| Cyclophosphamide | Refractory uveitis, nonnfectious ocular inflammation, ANCA-associated vasculitides |
| Chlorambucil | Serpiginous choroiditis, refractory uveitis, Behcet’s |
|
| T-cell inhibitors/calcineurin inhibitors |
| Cyclosporine | Serpiginous choroidopathy, Behcet’s, scleritis, rheumatoid arthritis, nonnfectious uveitis |
| Tacrolimus | The above indications but usually in conjunction with systemic corticosteroids or adjunct immunosuppressants |
| Rapamycin |
|
| Biologic agents |
| Etanercept | Juvenile idiopathic arthritis, noninfectious uveitis, ocular inflammatory disease |
| Infliximab | Refractory uveitis, childhood uveitis, Behcet’s |
| Adalimumab | Refractory uveitis, ankylosing spondylitis, juvenile idiopathic arthritis |
| Daclizumab | Juvenile idiopathic arthritis, recalcitrant ocular inflammation, birdshot chorioretinopathy |
| Rituximab | Primary Sjogren’s syndrome, thyroid eye disease, Wegener’s granulomatosis |
| Tocilizumab | Severe refractory posterior uveitis |
| Gevokizumab | Behcet’s |
|
| Other |
| Interferons | Behcet’s, noninfectious uveitis |
| Anakinra | Behcet’s, refractory juvenile idiopathic disease |
|
