Review Article

Helicobacter pylori Infection, Chronic Inflammation, and Genomic Transformations in Gastric MALT Lymphoma

Table 1

Ann Arbour clinical staging for gastric lymphoma.

StageLocalization

I EConfined within the gastric wall
II E1Involvement of stomach and contiguous lymph nodes
II E2Involvement of stomach and noncontiguous subdiaphragmatic lymph nodes
IIILymph nodes on both sides of the diaphragm
IVVisceral metastasis or second extranodal site

Subscripts that can be added to staging:
E: extranodal, when lymphoid tissue outside lymph nodes is involved.
X: is added when the largest diameter is above 10 cm (called bulky disease).
S: is added when the spleen is involved.
A or B: B is added when one of B symptoms is present, and A is for asymptomatic patients.