Dexmedetomidine Inhibits Inflammatory Reaction in Lung Tissues of Septic Rats by Suppressing TLR4/NF-κB Pathway

Figure 5

Effect of dexmedetomidine on TLR4 and MyD88 expression in lung tissues of septic rats by western blotting. Sham: sham operation group; CLP: cecal ligation and puncture operation group; Small: 5 μg/kg dexmedetomidine treatment group; Medium: 10 μg/kg dexmedetomidine treatment group; Large: 20 μg/kg dexmedetomidine treatment group. GAPDH: glyceraldehyde phosphate dehydrogenase. Data are expressed as mean±SD, 𝑛=8. ^∗𝑃<0.01, versus sham group; ^#𝑃<0.01, versus CLP group.

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