Lung-Derived Mediators Induce Cytokine Production in Downstream Organs via an NF-κB-Dependent Mechanism
Activation of NF-κB in MLEC exposed to control uncirculated perfusate, lung perfusate, and TNF-α/cytomix. (a) Representative western blot and (b) densitometry of P-p65 relative to GAPDH expression. (c) Activation of NF-κB employing phospho-p65 (Ser536) ELISA. (* versus control, ±SEM).