Increased Serum Levels and Chondrocyte Expression of Nesfatin-1 in Patients with Osteoarthritis and Its Relation with BMI, hsCRP, and IL-18

Figure 5

The relationships between serum nesfatin-1 levels and serum hsCRP, PIIANP levels and between synovial nesfatin-1 levels and synovial IL-18 levels. (a) A strong and statistically significant correlation was found between serum nesfatin-1 and hsCRP levels in OA patients (𝑟=0.593, 𝑃=0.00005); (b) there was no statistical correlation between serum nesfatin-1 and PIIANP levels (𝑟=−0.226, 𝑃=0.16); (c) statistically significant correlation was found between synovial nesfatin-1 and IL-18 levels 𝑟=0.560, 𝑃=0.0017.

(a)

(b)

(c)