Expression of Inflammation-Related Genes Is Altered in Gastric Tissue of Patients with Advanced Stages of NAFLD

Table 3

Correlations between inflammatory gene expression levels (dependent variable) and the following pathological conditions (independent variable).

Gene	Spearman correlation	𝑃 values	FDR significance (B-H pass test )
Advanced liver inflammation (score ≥ 3)
CCL3	0.45	0.041336	Yes
CCL4	0.47	0.035439	Yes
IL8	0.45	0.042123	Yes
CCR5	0.48	0.031463	Yes
IL8RB	0.50	0.024563	Yes
CCL21	0.50	0.024304	Yes
IFNA2	0.51	0.024371	Yes
IL19	0.51	0.020672	Yes
IL1F8	0.53	0.013993	Yes
Advanced steatosis (score ≥ 3)
IL1F10	0.45	0.043652	Yes
IL8RB	0.49	0.025506	Yes
NASH
CXCL12	−0.44	0.049062	Yes
CCL1	0.45	0.045748	Yes
CCR3	0.46	0.039522	Yes
CCR9	0.46	0.039522	Yes
IL5	0.44	0.049062	Yes
IL8RA	0.47	0.032636	Yes
IL8RB	0.44	0.049062	Yes
IL1RN	0.53	0.014784	Yes
IL9	0.53	0.014605	Yes
Fibrosis
C5	0.46	0.038905	Yes
SCYE1	0.48	0.030164	Yes
IL1RN	0.53	0.015503	Yes

Advanced liver inflammation (score ≥ 3) (𝑁=10), advanced steatosis (score ≥ 3) (𝑁=8), NASH (𝑁=13), fibrosis (𝑁=15). NASH: nonalcoholic steatohepatitis.