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Mediators of Inflammation
Volume 2013, Article ID 710239, 14 pages
http://dx.doi.org/10.1155/2013/710239
Research Article

Flavonoids and 5-Aminosalicylic Acid Inhibit the Formation of Neutrophil Extracellular Traps

1Institute for Medical Microbiology and Hygiene, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany
2Institute of Anatomy, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany

Received 16 August 2013; Revised 18 October 2013; Accepted 30 October 2013

Academic Editor: Magdalena Klink

Copyright © 2013 Tina Kirchner et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Figure S1. Antioxidants used in this study are not toxic and do not induce apoptosis in neutrophils.

Figure S2. Antioxidant treatment does not inhibit activation-induced degranulation of human neutrophils.

Figure S3. Antioxidant treatment does not inhibit chemotactic migration of human neutrophils.

Figure S4. DPI but not antioxidant treatment reduces phagocytic activity of stimulated human neutrophils.

  1. Supplementary Material