Paradoxical Glucose-Sensitizing yet Proinflammatory Effects of Acute ASP Administration in Mice

Table 2

Plasma lipids and cytokines.

Cytokine (unit)	Control (𝑛=8)	ASP (𝑛=7)
TG (mmol/L)	1.2±0.2	1.1±0.1
NEFA (mmol/L)	0.76±0.07	0.53±0.04^∗
IL-6 (pg/mL)	1.8±0.9	22.8±3.7^∗∗∗
IL-10 (pg/mL)	6.8±2.3	18.6±4.8^#
G-CSF (pg/mL)	38.8±7.7	70.2±12.9^#
GM-CSF (pg/mL)	14.3±2.5	29.3±5.9^∗
KC (pg/mL)	65.3±12.2	403.4±95.1^∗∗
MIP-1α (pg/mL)	3.2±0.7	6.76±1.2^∗
TNF-α (pg/mL)	39.6±4.4	105.0±24.1^∗
PAI-1 (ng/mL)	827±167	1382±84^∗∗
Leptin (𝜇g/mL)	16.1±4.0	6.5±2.2^∗

Plasma characteristics of mice, with/without ASP injection. Plasma lipids and cytokines were compared by 𝑡-tests. Results are expressed as mean ± sem where ^#𝑃=0.08, *𝑃<0.05, and **𝑃<0.01.