Cannabinoid Receptor 2 Protects against Acute Experimental Sepsis in Mice
Figure 2
GW405833 inhibits ConA-induced splenocytes proliferation partially via CB2R activation. (a) Splenocytes isolated from CB2R+/+ mice were treated vehicle or ConA (5 μg/mL) in the absence or presence of GW405833 (1–10 M) for 24 h. Splenocytes proliferation was detected by CCK-8. Data are means SD () and **. (b) Splenocytes isolated from CB2R+/+ and CB2R−/− mice were treated with ConA (5 g/mL) in the absence or presence of GW405833 (10 M) for 24 h. Splenocytes proliferation was detected by CCK-8. Data are means SD () and **.