Associations between Tissue Visfatin/Nicotinamide, Phosphoribosyltransferase (Nampt), Retinol Binding Protein-4, and Vaspin Concentrations and Insulin Resistance in Morbidly Obese Subjects

Table 3

Visfatin/Nampt, vaspin, and RBP-4 protein concentrations in different tissues ^¥.

Tissues; (ng/mg protein)	Normal; (𝑛=13)	Pre-Diabetic; (𝑛=12)	Diabetic; (𝑛=13)
Visfatin/Nampt
Subcutaneous adipose	11.3 ± 13.01^b	10.5 ± 10.11^b	14.8 ± 17.42^b
Omental adipose	11.5 ± 7.71^b	11.4 ± 7.42^b	17.5 ± 23.64^c*
Mesenteric adipose	10.5 ± 9.44^b	16.6 ± 17.23^b	11.7 ± 9.36^b
Liver	24.0 ± 7.85^a	22.5 ± 10.71^a	22.8 ± 7.50^a
Muscle	7.5 ± 4.81^b	12.4 ± 11.60^b	9.9 ± 8.77^b
RBP-4
Subcutaneous adipose	441.2 ± 83.75^c	408.5 ± 49.11^c	437.1 ± 63.37^c
Omental adipose	421.4 ± 67.46^c	420.0 ± 62.44^c	442.2 ± 65.96^c
Mesenteric adipose	353.9 ± 45.92^d	314.2 ± 49.40^d	348.3 ± 41.75^d
Liver	11880.2 ± 1008^a	11744.9 ± 791^a	11248.1 ± 1209^a
Muscle	638.2 ± 436.20^b	768.4 ± 443.50^b	530.4 ± 238.4^b
Vaspin
Subcutaneous adipose	0.66 ± 0.45^b	0.09 ± 0.01^b	0.90 ± 0.46^b
Omental adipose	0.57 ± 0.16^ab	2.26 ± 2.07^ab	1.07 ± 0.36^ab
Mesenteric adipose	0.23 ± 0.09^b	0.17 ± 0.01^b	0.67 ± 0.46^b
Liver	1.41 ± 0.18^a	3.05 ± 0.91^a*	2.17 ± 0.45^a*
Muscle	0.35 ± 0.05^b	1.38 ± 0.39^b	0.47 ± 0.08^b

¥Data are presented as means ± SD.
∗Means are significantly high within a row, P < 0.05.
abcdMeans within a column for an adipokine without a common superscript differ, P < 0.05.
RBP-4: retinol binding protein-4.