Research Article

The Effects of Proresolution of Ellagic Acid in an Experimental Model of Allergic Airway Inflammation

Figure 3

Effect of the therapeutic treatment with ellagic acid on lung inflammation and mucus secretion. Mice were treated with ellagic acid (10 mg/kg) or dexamethasone (1 mg/kg) or vehicle (water). One group of animals received vehicle (control group). Lung tissue sections were obtained at protocol day 21 and stained with H&E (original magnification: 200x) and the inflammation was quantified (a). Lugs tissue sections were also stained with PAS reagent (original magnification: 400x) and bronchial PAS-positive cells were quantified (b). Arrows indicate examples of mucus-containing (magenta) goblet cells. Results represent the mean ± SEM of two or more independent experiments with three mice per group. compared with control group; compared with ovalbumin + vehicle group. Br: bronchus and V: venule.
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(a)
863198.fig.003b
(b)