Regulation of Immune Cell Infiltration into the CNS by Regional Neural Inputs Explained by the Gate Theory

<table>The fifth lumber cord is a gateway into the CNS. A cross section of the fifth lumber (L5) cord (a) and actual cell numbers of mononuclear cells accumulated in each lumber cord segment (b) at a preclinical phase of EAE (5 days after pathogenic Th17 transfer). A 3D picture based on ten serial sections of L5 is also shown.</table>

Mediators of Inflammation

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Figure 2

Figure 2: Regulation of Immune Cell Infiltration into the CNS by Regional Neural Inputs Explained by the Gate Theory 