Research Article

Therapeutic Effects of the Superoxide Dismutase Mimetic Compound Me2DO2A on Experimental Articular Pain in Rats

Figure 3

Effect of MnL4, H2 L4, and gabapentin (acutely administered) on monoiodoacetate- (MIA-) induced unilateral osteoarthritis. MIA was injected in the left posterior tibiotarsal articulation 14 days before pain evaluation by the paw pressure test. Molecules or saline was administered i.p. at time 0 and measures were performed at time 15, 30, 45, and 60 min. Values are the mean ± s.e.m. of 6 animals. * versus the ipsilateral paw of MIA + saline group, versus MIA + MnL4 at the same time.
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