Inflammatory Mediator Profiling Reveals Immune Properties of Chemotactic Gradients and Macrophage Mediator Production Inhibition during Thioglycollate Elicited Peritoneal Inflammation

Table 3

Fold increases of inflammatory mediator productions in cell culture media and lysates of murine peritoneal macrophages following LPS treatment for 24 h in vitro.

	Fold increase
	Culture media (A, 𝑛=2)	Cell lysates (B, 𝑛=4)
IL-11	1.66±0.03	4.65±1.30
OSM	1.78±0.10	11.91±3.55
IL-7	1.90±0.16	8.75±2.82
SCF	1.94±0.15	11.86±3.30
Lymphotactin	1.98±0.22	6.14±1.61
FGF-9	2.22±0.23	2.48±1.10
IL-10	3.29±0.08	7.71±2.33
IL-12p70	4.36±0.93	2.20±0.96
VEGF-A	4.81±1.36	2.72±0.53
KC/GRO	6.21±2.87	17.28±5.00
RANTES**	8.93±3.00	1.87±0.55
IL-1α	10.44±2.36	225.12±126.41
MIP-2	12.61±6.43	25.01±11.05
MCP-1	14.17±0.80	12.95±1.56
MCP-3**	17.69±1.20	11.44±0.98
IFN-γ	17.94±1.23	29.28±11.75
TIMP-1**	20.87±3.31	10.32±0.97
TNF-α	20.93±8.58	42.44±17.07
IP-10	44.65±14.11	28.17±7.03
MCP-5	47.69±23.83	3.72±0.32
IL-6*	81.43±11.59	33.04±4.43
MIP-1β	127.89±103.35	20.52±9.87

* 𝑃<0.01 A versus B.
** 𝑃<0.05 A versus B.
All other groups, 𝑃>0.05.