Review Article

Vitreous Inflammation Associated with Intravitreal Anti-VEGF Pharmacotherapy

Table 1

Clinical characteristics of noninfectious versus infectious endophthalmitis.

Noninfectious endophthalmitisInfectious endophthalmitis

Pain± [14, 17, 20]++ [14]
Onset<1 day [10, 14, 16, 20, 21] to 1 week [11, 15, 17, 22]2.5 days (range: 1–6 days) [14, 15, 23]
SignsBlurred vision [11], anterior segment inflammation greater than posterior inflammation [10, 17, 18, 21, 22]Decreased vision, severe anterior segment reaction (fibrin and hypopyon), and vitritis [14]
Time to resolution2–12 weeks [11, 15, 17, 18, 20, 24]Extremely variable
PrognosisPreinjection visual acuity [10, 11, 14, 1618, 21, 22]Severely depressed [22]