Research Article

Ubiquitous Transgenic Overexpression of C-C Chemokine Ligand 2: A Model to Assess the Combined Effect of High Energy Intake and Continuous Low-Grade Inflammation

Figure 7

We found no significant differences among strains in the appearance of liver tissue when mice were fed a chow diet (left column (a), (c), (e); transgenic, wild-type, and knockout mice resp.). Representative micrographs show in the right column that a high fat diet produces steatosis in transgenic mice (b), dispersed lipid droplets in the liver of wild type mice (d), and no change in knockout mice (f).
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(a)
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(b)
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(c)
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(d)
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(e)
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(f)