Anti-Inflammatory Mechanism of Polyunsaturated Fatty Acids in Helicobacter pylori-Infected Gastric Epithelial Cells

Figure 1

Time-dependent production of IL-8 and effects of PUFAs on H. pylori-infected AGS cells. (a) AGS cells were cultured with H. pylori for the indicated time periods (2, 4, 8, and 12 h) and IL-8 levels in the medium was measured by enzyme-linked immunosorbent assay. (b) AGS cells were pretreated with individual fatty acid (100 𝜇M) for 24 h and cultured with H. pylori for 4 h. Each bar represents mean ± S.E. of four separate experiments. ^∗𝑃<0.01 versus None; ⁺𝑃<0.01 versus control.

(a)

(b)