Effect of Tumor Necrosis Factor Family Member LIGHT (TNFSF14) on the Activation of Basophils and Eosinophils Interacting with Bronchial Epithelial Cells
Effects of LIGHT on the release of MMP-9 in the coculture of basophils and BEAS-2B cells. Confluent BEAS-2B cells (1 × 105 cells) and basophils (3 × 105 cells) were cultured either together or separately with LIGHT (0–100 ng/mL) for 24 h. Release of MMP-9 in culture supernatants was measured by Milliplex human MMP panel assay. Results are expressed as the mean plus SEM of three independent experiments with three blood samples. *, ***. BAS: basophils; BS: BEAS-2B cells; CO: coculture of basophils and BEAS-2B cells.
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