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Mediators of Inflammation
Volume 2014, Article ID 165742, 9 pages
http://dx.doi.org/10.1155/2014/165742
Research Article

Elevated Plasma IL-37, IL-18, and IL-18BP Concentrations in Patients with Acute Coronary Syndrome

1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China
2Department of Cardiology, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China
3Institute of Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
4Department of Ultrasound, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China

Received 7 November 2013; Revised 19 January 2014; Accepted 20 January 2014; Published 6 March 2014

Academic Editor: Alex Kleinjan

Copyright © 2014 Qingwei Ji et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. F. Nold, C. A. Nold-Petry, J. A. Zepp, B. E. Palmer, P. Bufler, and C. A. Dinarello, “IL-37 is a fundamental inhibitor of innate immunity,” Nature Immunology, vol. 11, no. 11, pp. 1014–1022, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. D. Boraschi, D. Lucchesi, S. Hainzl et al., “IL-37: a new anti-inflammatory cytokine of the IL-1 family,” European Cytokine Network, vol. 22, no. 3, pp. 127–147, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. G. Pan, P. Risser, W. Mao et al., “IL-1H, an interleukin 1-related protein that binds IL-18 receptor/IL-1Rrp,” Cytokine, vol. 13, no. 1, pp. 1–7, 2001. View at Publisher · View at Google Scholar · View at Scopus
  4. H. Kirii, T. Niwa, Y. Yamada et al., “Lack of interleukin-1β decreases the severity of atherosclerosis in ApoE-deficient mice,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 23, no. 4, pp. 656–660, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. F. Merhi-Soussi, B. R. Kwak, D. Magne et al., “Interleukin-1 plays a major role in vascular inflammation and atherosclerosis in male apolipoprotein E-knockout mice,” Cardiovascular Research, vol. 66, no. 3, pp. 583–593, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. R. de Nooijer, J. H. von der Thüsen, C. J. Verkleij et al., “Overexpression of IL-18 decreases intimal collagen content and promotes a vulnerable plaque phenotype in apolipoprotein-E-deficient mice,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 24, no. 12, pp. 2313–2319, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. Z. Mallat, P. Henry, R. Fressonnet et al., “Increased plasma concentrations of interleukin-18 in acute coronary syndromes,” Heart, vol. 88, no. 5, pp. 467–469, 2002. View at Publisher · View at Google Scholar · View at Scopus
  8. K. Oboki, T. Ohno, N. Kajiwara et al., “IL-33 is a crucial amplifier of innate rather than acquired immunity,” Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 43, pp. 18581–18586, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Wasserman, J. Ben-Shoshan, M. Entin-Meer, S. Maysel-Auslender, H. Guzner-Gur, and G. Keren, “Interleukin-33 augments Treg cell levels: a flaw mechanism in atherosclerosis,” The Israel Medical Association Journal, vol. 14, no. 10, pp. 620–623, 2012. View at Google Scholar
  10. A. M. Miller, D. Xu, D. L. Asquith et al., “IL-33 reduces the development of atherosclerosis,” The Journal of Experimental Medicine, vol. 205, no. 2, pp. 339–346, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. S. Sharma, N. Kulk, M. F. Nold et al., “The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines,” The Journal of Immunology, vol. 180, no. 8, pp. 5477–5482, 2008. View at Google Scholar · View at Scopus
  12. E. N. McNamee, J. C. Masterson, P. Jedlicka et al., “Interleukin 37 expression protects mice from colitis,” Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 40, pp. 16711–16716, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. N. Sakai, H. L. van Sweringen, R. M. Belizaire et al., “Interleukin-37 reduces liver inflammatory injury via effects on hepatocytes and non-parenchymal cells,” Journal of Gastroenterology and Hepatology, vol. 27, no. 10, pp. 1609–1616, 2012. View at Publisher · View at Google Scholar
  14. C. Li, P. Zhao, X. Sun, Y. Che, and Y. Jiang, “Elevated levels of cerebrospinal fluid and plasma interleukin-37 in patients with guillain-barre syndrome,” Mediators of Inflammation, vol. 2013, Article ID 639712, 9 pages, 2013. View at Publisher · View at Google Scholar
  15. C. Li, H. Ji, Y. Cai et al., “Serum interleukin-37 concentrations and HBeAg seroconversion in chronic HBV patients during telbivudine treatment,” Journal of Interferon & Cytokine Research, vol. 33, no. 10, pp. 612–618, 2013. View at Publisher · View at Google Scholar
  16. L. Song, F. Qiu, Y. Fan et al., “Glucocorticoid regulates interleukin-37 in systemic lupus erythematosus,” Journal of Clinical Immunology, vol. 33, no. 1, pp. 111–117, 2013. View at Publisher · View at Google Scholar
  17. Q.-W. Ji, M. Guo, J.-S. Zheng et al., “Downregulation of T helper cell type 3 in patients with acute coronary syndrome,” Archives of Medical Research, vol. 40, no. 4, pp. 285–293, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. Y. Lin, Y. Huang, Z. Lu et al., “Decreased plasma IL-35 levels are related to the left ventricular ejection fraction in coronary artery diseases,” PloS ONE, vol. 7, no. 12, Article ID e52490, 2012. View at Publisher · View at Google Scholar
  19. G. G. Gensini, “A more meaningful scoring system for determining the severity of coronary heart disease,” The American Journal of Cardiology, vol. 51, no. 3, 606 pages, 1983. View at Publisher · View at Google Scholar · View at Scopus
  20. C. Kragelund, B. Grønning, L. Køber, P. Hildebrandt, and R. Steffensen, “N-terminal pro-B-type natriuretic peptide and long-term mortality in stable coronary heart disease,” The New England Journal of Medicine, vol. 352, no. 7, pp. 666–675, 2005. View at Publisher · View at Google Scholar · View at Scopus
  21. M. Weber, O. Bazzino, J. L. N. Estrada et al., “N-terminal B-type natriuretic peptide assessment provides incremental prognostic information in patients with acute coronary syndromes and normal troponin T values upon admission,” Journal of the American College of Cardiology, vol. 51, no. 12, pp. 1188–1195, 2008. View at Publisher · View at Google Scholar · View at Scopus
  22. C. R. Narins, D. A. Lin, P. B. Burton, Z.-G. Jin, and B. C. Berk, “Interleukin-18 and interleukin-18 binding protein levels before and after percutaneous coronary intervention in patients with and without recent myocardial infarction,” The American Journal of Cardiology, vol. 94, no. 10, pp. 1285–1287, 2004. View at Publisher · View at Google Scholar · View at Scopus
  23. W. Maier, L. A. Altwegg, R. Corti et al., “Inflammatory markers at the site of ruptured plaque in acute myocardial infarction: locally increased interleukin-6 and serum amyloid A but decreased C-reactive protein,” Circulation, vol. 111, no. 11, pp. 1355–1361, 2005. View at Publisher · View at Google Scholar · View at Scopus
  24. A. Aggarwal, D. J. Schneider, E. F. Terrien, B. E. Sobel, and H. L. Dauerman, “Increased coronary arterial release of interleukin-1 receptor antagonist and soluble CD40 ligand indicative of inflammation associated with culprit coronary plaques,” The American Journal of Cardiology, vol. 93, no. 1, pp. 6–9, 2004. View at Publisher · View at Google Scholar · View at Scopus
  25. T. Inoue, T. Kato, T. Uchida et al., “Local release of C-reactive protein from vulnerable plaque or coronary arterial wall injured by stenting,” Journal of the American College of Cardiology, vol. 46, no. 2, pp. 239–245, 2005. View at Publisher · View at Google Scholar · View at Scopus
  26. Y.-G. Ko, J.-H. Jung, S. Park et al., “Inflammatory and vasoactive factors in the aspirate from the culprit coronary artery of patients with acute myocardial infarction,” International Journal of Cardiology, vol. 112, no. 1, pp. 66–71, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. S. L. Taylor, B. R. Renshaw, K. E. Garka, D. E. Smith, and J. E. Sims, “Genomic organization of the interleukin-1 locus,” Genomics, vol. 79, no. 5, pp. 726–733, 2002. View at Publisher · View at Google Scholar · View at Scopus
  28. D. J. Grainger, P. R. Kemp, J. C. Metcalfe et al., “The serum concentration of active transforming growth factor-β is severely depressed in advanced atherosclerosis,” Nature Medicine, vol. 1, no. 1, pp. 74–79, 1995. View at Publisher · View at Google Scholar · View at Scopus
  29. A.-K. Robertson and G. K. Hansson, “T cells in atherogenesis: for better or for worse?” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 26, no. 11, pp. 2421–2432, 2006. View at Publisher · View at Google Scholar · View at Scopus
  30. E. L. Gautier, T. Huby, F. Saint-Charles et al., “Conventional dendritic cells at the crossroads between immunity and cholesterol homeostasis in atherosclerosis,” Circulation, vol. 119, no. 17, pp. 2367–2375, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. H. Methe, S. Brunner, D. Wiegand, M. Nabauer, J. Koglin, and E. R. Edelman, “Enhanced T-helper-1 lymphocyte activation patterns in acute coronary syndromes,” Journal of the American College of Cardiology, vol. 45, no. 12, pp. 1939–1945, 2005. View at Publisher · View at Google Scholar · View at Scopus
  32. R. E. Eid, D. A. Rao, J. Zhou et al., “Interleukin-17 and interferon-γ are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells,” Circulation, vol. 119, no. 10, pp. 1424–1432, 2009. View at Publisher · View at Google Scholar · View at Scopus
  33. A. Hermansson, D. K. Johansson, D. F. J. Ketelhuth, J. Andersson, X. Zhou, and G. K. Hansson, “Immunotherapy with tolerogenic apolipoprotein B-100-loaded dendritic cells attenuates atherosclerosis in hypercholesterolemic mice,” Circulation, vol. 123, no. 10, pp. 1083–1091, 2011. View at Publisher · View at Google Scholar · View at Scopus
  34. K. Yu, P. Zhu, Q. Dong et al., “Thymic stromal lymphopoietin attenuates the development of atherosclerosis in ApoE-/- mice,” Journal of the American Heart Association, vol. 2, no. 5, Article ID e000391, 2013. View at Publisher · View at Google Scholar
  35. Z. Mallat, A. Corbaz, A. Scoazec et al., “Expression of interleukin-18 in human atherosclerotic plaques and relation to plaque instability,” Circulation, vol. 104, no. 14, pp. 1598–1603, 2001. View at Publisher · View at Google Scholar · View at Scopus
  36. R. Elhage, J. Jawien, M. Rudling et al., “Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice,” Cardiovascular Research, vol. 59, no. 1, pp. 234–240, 2003. View at Publisher · View at Google Scholar · View at Scopus
  37. Z. Mallat, A. Corbaz, A. Scoazec et al., “Interleukin-18/interleukin-18 binding protein signaling modulates atherosclerotic lesion development and stability,” Circulation Research, vol. 89, no. 7, pp. E41–E45, 2001. View at Publisher · View at Google Scholar · View at Scopus
  38. A. J. Puren, G. Fantuzzi, Y. Gu, M. S. Su, and C. A. Dinarello, “Interleukin-18 (IFNγ-inducing factor) induces IL-8 and IL-1β via TNFα production from non-CD14+ human blood mononuclear cells,” The Journal of Clinical Investigation, vol. 101, no. 3, pp. 711–721, 1998. View at Publisher · View at Google Scholar · View at Scopus
  39. R. A. Kelly and T. W. Smith, “Cytokines and cardiac contractile function,” Circulation, vol. 95, no. 4, pp. 778–781, 1997. View at Publisher · View at Google Scholar · View at Scopus
  40. K. A. Krown, M. T. Page, C. Nguyen et al., “Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes: involvement of the sphingolipid signaling cascade in cardiac cell death,” The Journal of Clinical Investigation, vol. 98, no. 12, pp. 2854–2865, 1996. View at Publisher · View at Google Scholar · View at Scopus
  41. J. Koglin, D. J. Granville, T. Glysing-Jensen et al., “Attenuated acute cardiac rejection in NOS2 -/- recipients correlates with reduced apoptosis,” Circulation, vol. 99, no. 6, pp. 836–842, 1999. View at Publisher · View at Google Scholar · View at Scopus
  42. I. Jeremias, C. Kupatt, A. Martin-Villalba et al., “Involvement of CD95/Apo1/Fas in cell death after myocardial ischemia,” Circulation, vol. 102, no. 8, pp. 915–920, 2000. View at Publisher · View at Google Scholar · View at Scopus
  43. B. Felzen, M. Shilkrut, H. Less et al., “Fas (CD95/Apo-1)-mediated damage to ventricular myocytes induced by cytotoxic T lymphocytes from perforin-deficient mice: a major role for inositol 1,4,5-trisphosphate,” Circulation Research, vol. 82, no. 4, pp. 438–450, 1998. View at Publisher · View at Google Scholar · View at Scopus
  44. M. Hartford, O. Wiklund, L. M. Hultén et al., “Interleukin-18 as a predictor of future events in patients with acute coronary syndromes,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 30, no. 10, pp. 2039–2046, 2010. View at Publisher · View at Google Scholar · View at Scopus
  45. N. K. Banda, A. Vondracek, D. Kraus et al., “Mechanisms of inhibition of collagen-induced arthritis by murine IL-18 binding protein,” The Journal of Immunology, vol. 170, no. 4, pp. 2100–2105, 2003. View at Google Scholar · View at Scopus
  46. P. Bufler, T. Azam, F. Gamboni-Robertson et al., “A complex of the IL-1 homologue IL-1F7b and IL-18-binding protein reduces IL-18 activity,” Proceedings of the National Academy of Sciences of the United States of America, vol. 99, no. 21, pp. 13723–13728, 2002. View at Publisher · View at Google Scholar · View at Scopus