The Inhibitory Effect of PIK-75 on Inflammatory Mediator Response Induced by Hydrogen Peroxide in Feline Esophageal Epithelial Cells

Figure 5

Effect of PIK-75 on p-Akt activation in feline EECs stimulated by H₂O₂. Representative Western blot analyses of p-Akt expressed in feline EECs (). EECs were pretreated with PIK-75 at different concentrations, followed by the stimulation with H₂O₂ (300 μM, 30 minutes). t-Akt expression was used as a reference. Data are expressed as means ± S.E of four experiments (Student’s t-test; versus control, versus H₂O₂ alone).