Impact of Wines and Wine Constituents on Cyclooxygenase-1, Cyclooxygenase-2, and 5-Lipoxygenase Catalytic Activity

Table 1

Inhibition of COX-1, COX-2 (concentration of wine: 5 mL/L), and 5-LOX (concentration of wine: 18.87 mL/L) enzymatic activity by red wines.

Number	Variety and origin	Inhibition against blank (%)
		COX-1	COX-2	5-LOX
1	Pinot Noir, Czech Rep.	46.13	33.25	79.96
2	Pinot Noir, Czech Rep.	90.25	29.23	77.61
3	Pinot Noir, Austria	70.05	29.20	82.74
4	Pinot noir, France	94.04	52.23	85.01
5	Pinot noir, France	85.57	22.78	84.21
6	Cabernet Sauvignon, Italy	73.52	12.21	81.92
7	Cabernet Sauvignon, Italy	87.20	23.81	83.81
8	Cabernet Sauvignon, France	92.16	37.60	80.96
9	Cabernet Sauvignon, France	92.98	43.14	82.38
10	Cabernet Sauvignon, Czech Rep.	81.42	42.14	77.59
11	Cabernet Sauvignon, Czech Rep.	48.95	34.95	71.36
12	Cabernet Sauvignon, Georgia	77.57	13.68	83.86
13	Cabernet Moravia, Czech Rep.	52.67	13.43	82.56
14	Cabernet Moravia, Czech Rep.	73.68	26.91	85.39
15	Saperavi, Georgia	90.98	25.33	84.86
16	Saperavi, Georgia	90.74	43.73	84.33
17	Saperavi, Georgia	90.31	53.24	80.65
18	Saperavi, Georgia	82.30	35.23	88.29
19	Saperavi, Georgia	38.41	−7.23	62.24
20	Saperavi, Georgia	84.09	25.42	78.68
21	Saperavi, Georgia	95.48	52.95	73.08
22	Saperavi, Georgia	95.13	63.86	80.15
23	Saperavi, Georgia	89.07	28.99	77.79
24	Saperavi + Saperavi Budeshuriseburi, Georgia	92.65	40.27	71.65
25	Saperavi + Saperavi Budeshuriseburi, Georgia	94.35	45.03	72.89
26	Alexandrouli, Georgia	82.27	22.28	79.02

Data is presented as the mean value.