Research Article

Lipoprotein Lipase and PPAR Alpha Gene Polymorphisms, Increased Very-Low-Density Lipoprotein Levels, and Decreased High-Density Lipoprotein Levels as Risk Markers for the Development of Visceral Leishmaniasis by Leishmania infantum

Table 1

Levels of serum lipids in individuals exposed to Leishmania infantum from endemic area.

Lipids Infected symptomatic individuals Infected asymptomatic individuals Noninfected individuals value
mg/dLmg/dLmg/dL

TC17121.2 ± 34.628143.0 ± 42.136139.9 ± 36.10.152
LDL-C1759.5 ± 30.82885.5 ± 42.23677.1 ± 36.00.083
HDL-C1738.3 ± 4.3*2839.0 ± 5.8*3643.0 ± 7.20.012
TAG1728169.1 ± 62.736157.9 ± 67.60.013
VLDL-C172833.9 ± 12.43631.6 ± 13.50.013

TC = total cholesterol; LDL-C = low-density lipoprotein cholesterol; HDL-C = density lipoprotein cholesterol; TAG = triacylglycerol; VLDL = very-low-density lipoprotein cholesterol. Lipid values expressed as the mean ± SD. value analyzed by ANOVA test with the Student Newman-Keuls posttest. versus noninfected individuals; versus infected asymptomatic individuals. values in bold indicate statistically significant differences.