Adipokines NUCB2/Nesfatin-1 and Visfatin as Novel Inflammatory Factors in Chronic Obstructive Pulmonary Disease

Table 2

Correlations between adipokines and other parameters in patients with COPD (𝑛=43).

	NUCB2/nesfatin-1	Visfatin
FEV1 (% pred)	rho = 0.097	𝑟=0.127
	𝑃=0.535	𝑃=0.422
FENO0.05 (ppb)	rho = −0.035	𝑟=0.040
	𝑃=0.823	𝑃=0.802
Hb-𝐷L,CO/𝑉𝐴 (% pred)	rho = −0.103	𝑟=−𝟎.𝟑𝟔𝟗
	𝑃=0.512	𝑃=𝟎.𝟎𝟏𝟔
Emphysema percentage (%)	rho = 0.076	𝑟=0.204
	𝑃=0.626	𝑃=0.194
IL-6 (pg/mL)	rho = 0.401	𝑟=𝟎.𝟑𝟒𝟏
	𝑃=𝟎.𝟎𝟎𝟖	𝑃=𝟎.𝟎𝟐𝟕
IL-8 (pg/mL)	rho = 0.321	𝑟=0.121
	𝑃=𝟎.𝟎𝟑𝟔	𝑃=0.443
TNF-α (pg/mL)	rho = 0.329	𝑟=𝟎.𝟑𝟎𝟓
	𝑃=𝟎.𝟎𝟑𝟑	𝑃=𝟎.𝟎𝟓𝟐

The distribution of nesfatin-1 was skewed while visfatin was normally distributed; therefore Spearman’s rho and Pearson’s 𝑟 were used to analyze the correlations of NUCB2/nesfatin-1 and visfatin, respectively, to the other parameters presented.
FEV₁: forced expiratory volume in 1 second; FENO_0.05: fractional exhaled nitric oxide concentration at exhalation flow rate of 50 mL/s; Hb-𝐷_L,CO/𝑉_𝐴: diffusing capacity for carbon monoxide per unit of alveolar volume standardized for haemoglobin; IL: interleukin; TNF: tumor necrosis factor.