Review Article

On the Significance of New Biochemical Markers for the Diagnosis of Premature Labour

Table 1

Characteristics of the alarmines important for premature labor pathogenesis.

AlarmineReceptorAction

HMGB1TLR (toll-like receptor)
RAGE (receptor for advanced glycation end products)
Inflammatory response (NF-B activation)
Tissue regeneration

Heat shock proteins:
HSP 60
HSP 70
HSP 72
HSP 90
TLR
RAGE
Cytoprotection
Antigen presentation
Macrophage and lymphocyte activation
Inflammatory response (NF-B activation)