On the Significance of New Biochemical Markers for the Diagnosis of Premature Labour

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td align="left">Receptor</td><td align="left">Location</td><td align="left">Activation effect</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td align="left">Native RAGE</td><td align="left">Cell surface: <br/>Phagocytes <br/>Hepatocytes <br/>Endothelium <br/>Smooth muscles of blood vessel media <br/>Nervous system cells <br/>Glomeruli mesangial cells</td><td align="left">Induction and maintenance of inflammatory response</td></tr><tr><td align="center" colspan="3"><hr/></td></tr><tr><td align="left">Dominating negative RAGE (dnRAGE)</td><td align="left">Cell surface</td><td align="left">Signal transduction suppression by concentration of ligands on cell surface</td></tr><tr><td align="center" colspan="3"><hr/></td></tr><tr><td align="left">Soluble secretory RAGE (sRAGE) <br/>Endogenous secretory RAGE (esRAGE)</td><td align="left">Ligand-RAGE complexes released to circulating blood, degraded in liver and spleen</td><td align="left">Binding of advanced glycation end products</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Mediators of Inflammation

tab2

Table 2

Table 2: On the Significance of New Biochemical Markers for the Diagnosis of Premature Labour 